Baldridge Lab

Biological Chemistry
University of Michigan Medical School

Current Lab

All Lab Members »
Sagar Lahiri

Sagar Lahiri, PhD

Postdoctoral Researcher

Location: 3200 MSRB3
Lab Phone: (734) 936-3440
Email: lahiris@umich.edu

Research Gate    Google Scholar   

Sagar obtained his BSc.and MSc in microbiology from Calcutta University, Kolkata, India. He finished his PhD in biochemistry at the Indian Institute of Chemical Biology, Kolkata, India in 2014. His graduate research focused on the structure-function relationship of the enzymes involved in trehalose metabolism in yeast. In 2015 he joined the Department of Cell and Developmental Biology at U of M where he studied cellular traffic at the Trans Golgi Network. In the Baldridge lab, he is working to establish the principles of substrate recognition by ERAD.

Awards and Honors

  • Awarded national scholarships of merit in recognition of the high position secured in the Madhyamik Pariksha (10th standard) from West Bengal (2000)
  • Winner of the B.S. Narasingha Rao best poster in Enzymology at the scientific sessions of 79th annual general meeting of ‘The Society of Biological Chemists (India)’ held at Indian Institute of Science, Bangalore (2010)
  • Awarded Senior Research Fellowship (CSIR/SRF) from Council of Scientific & Industrial Research, New Delhi, India (2011)
  • Selected for Senior Research Fellowship (CSIR/SRF Extended) from Council of Scientific & Industrial Research, New Delhi, India (2014)

Publications

Enzymatic attributes of an l-isoaspartyl methyltransferase from Candida utilis and its role in cell survival.

Banerjee S, Dutta T, Lahiri S, Sengupta S, Gangopadhyay A, Kumar Karri S, Chakraborty S, Bhattacharya D, Ghosh AK

Biochemistry and Biophysics Reports, 2015, 4, 59-75

View on PubMed »

Purification, characterization, sequencing and molecular cloning of a novel cysteine methyltransferase that regulates trehalose-6-phosphate synthase from Saccharomyces cerevisiae.

Sengupta S, Banerjee S, Lahiri S, Dutta T, Dhar TK, Ghosh AK

Biochimica Et Biophysica Acta, 2014, 1840 (6), 1861-71

View on PubMed »

Enzymatic and regulatory attributes of trehalose-6-phosphate phosphatase from Candida utilis and its role during thermal stress.

Lahiri S, Banerjee S, Dutta T, Sengupta S, Dey S, Roy R, Sengupta D, Chattopadhyay K, Ghosh AK

Journal of Cellular Physiology, 2014, 229 (9), 1245-55

View on PubMed »

Purification and characterization of a trehalase-invertase enzyme with dual activity from Candida utilis.

Lahiri S, Basu A, Sengupta S, Banerjee S, Dutta T, Soren D, Chattopadhyay K, Ghosh AK

Archives of Biochemistry and Biophysics, 2012, 522 (2), 90-9

View on PubMed »

Methylation dependent enhancement of trehalose production in Candida utilis.

Sengupta S, Lahiri S, Banerjee S, Dutta T, Dhar TK, Ghosh AK

Carbohydrate Research, 2012, 361, 175-81

View on PubMed »

Regulation of enzymatic activity by deamidation and their subsequent repair by protein L-isoaspartyl methyl transferase.

Dutta T, Banerjee S, Soren D, Lahiri S, Sengupta S, Rasquinha JA, Ghosh AK

Applied Biochemistry and Biotechnology, 2012, 168 (8), 2358-75

View on PubMed »

Possible regulation of trehalose metabolism by methylation in Saccharomyces cerevisiae.

Sengupta S, Chaudhuri P, Lahiri S, Dutta T, Banerjee S, Majhi R, Ghosh AK

Journal of Cellular Physiology, 2011, 226 (1), 158-64

View on PubMed »

Arginine mediated purification of trehalose-6-phosphate synthase (TPS) from Candida utilis: Its characterization and regulation.

Sengupta S, Lahiri S, Banerjee S, Bashistha B, Ghosh AK

Biochimica Et Biophysica Acta, 2011, 1810 (12), 1346-54

View on PubMed »

Studies on substrate specificity and activity regulating factors of trehalose-6-phosphate synthase of Saccharomyces cerevisiae.

Chaudhuri P, Basu A, Sengupta S, Lahiri S, Dutta T, Ghosh AK

Biochimica Et Biophysica Acta, 2009, 1790 (5), 368-74

View on PubMed »